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	<title>Comments on: Interim Analysis Part 1: Role of the Data Monitoring Committee</title>
	<link>http://pharmaweblog.com/blog/2006/08/08/interim-analysis-part-1-role-of-the-data-monitoring-committee/</link>
	<description>Pharmaceutical and biotech science and business</description>
	<pubDate>Wed, 20 Aug 2008 11:02:56 +0000</pubDate>
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		<title>by: Pharma&#8217;s Cutting Edge &#187; ADAPT: The Wrong Way to Stop a Clinical Trial</title>
		<link>http://pharmaweblog.com/blog/2006/08/08/interim-analysis-part-1-role-of-the-data-monitoring-committee/#comment-31</link>
		<pubDate>Wed, 22 Nov 2006 22:22:59 +0000</pubDate>
		<guid>http://pharmaweblog.com/blog/2006/08/08/interim-analysis-part-1-role-of-the-data-monitoring-committee/#comment-31</guid>
					<description>[...] The actions to stop the ADAPT trial are clearly antithetical to widely accepted prinicples for conducting interim safety analyses, as I have described in a previous blog post and recently published white paper.  It&amp;#8217;s shocking that the U.S.&amp;#8217;s leading health-research authority would be responsible for such blatant scientific misconduct.  It&amp;#8217;s the type of action that should result in a GAO investigation and in the loss of job for those found to be chiefly responsible.  Share with the world: These icons link to social bookmarking sites where readers can share and discover new web pages. [...]</description>
		<content:encoded><![CDATA[<p>[&#8230;] The actions to stop the ADAPT trial are clearly antithetical to widely accepted prinicples for conducting interim safety analyses, as I have described in a previous blog post and recently published white paper.  It&#8217;s shocking that the U.S.&#8217;s leading health-research authority would be responsible for such blatant scientific misconduct.  It&#8217;s the type of action that should result in a <acronym title="General Accounting Office">GAO</acronym> investigation and in the loss of job for those found to be chiefly responsible.  Share with the world: These icons link to social bookmarking sites where readers can share and discover new web pages. [&#8230;]
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